Publications
WIRES RNA Cover Image
Publications
- Al-Husini, N., Vaishnu, A., Aretakis, J.R., Gega, A., Bitar, O., Nunez, N., Bejdokht, J.F., Schrader, J.M. mRNA decay impacts the Caulobacter crescentus cell cycle. Manuscript in preparation.
- Nandana, V., Schrader, J.M. Roles of liquid-liquid phase separation in bacterial RNA metabolism. Review, In preparation.
- Muthunayake, N.S., Al-Husini, N., and Schrader, J. M. Differential centrifugation to enrich Bacterial Ribonucleoprotein bodies (BR-bodies) from Caulobacter crescentus. Accepted, STAR Protocols.
- Bharmal, M.-H.M., Aretakis, J.M., Schrader, J.M. An improved Caulobacter crescentus operon annotation based on transcriptome data Accepted, MRA.
- Bharmal, M.-H.M., Schrader, J.M. A combinatorial model predicts leaderless mRNA start codon selection in C. crescentus. BioRxiv, 2020.
- Muthunayake, N.S., Tomares, D. T. , Childers, W. S., and Schrader, J. M. Phase-Separated Bacterial Ribonucleoprotein Bodies (BR-bodies) Organize mRNA Decay. WIREs RNA 2020.
- Al-Husini, N., D. T. Tomares, Z. Pfaffenberger, N. S. Muthunayake, M. A. Samad, T. Zuo, O. Bitar, J. R. Aretakis, M.-H. M. Bharmal, A. Gega, J. S. Biteen, W. S. Childers and J. M. Schrader. BR-bodies provide selectively permeable condensates that stimulate mRNA decay and prevent release of decay intermediates. Accepted, Molecular Cell 2020. BioRxiv, 2019.
- Munoz-Dorado, J., A. Moraleda-Muñoz, F. J. Marcos-Torres, F. J. Contreras-Moreno, A. B. Martin-Cuadrado, J. M. Schrader, P. I. Higgs and J. Perez. Transcriptome dynamics of the Myxococcus xanthus multicellular developmental program. eLife, 2019.
- Aretakis, J.R., Gega, A., Schrader, J.M. Absolute measurements of mRNA translation in C. crescentus reveal important fitness costs of vitamin B12 scavenging. mSystems, 2019, BioRxiv, 2019.
- Aretakis, J.R, Al-Husini, N., Schrader, J.M. Methodology for ribosome profiling of key stages of the Caulobacter crescentus cell cycle. Methods in Enzymology, 2018.
- Al-Husini, N., Tomares, D.T., Bitar, O., Childers, W.S., Schrader, J.M. α-proteobacterial RNA degradosomes assemble liquid-liquid phase separated RNP bodies. Molecular Cell, 2018.
- Uhlenbeck, O.C. and Schrader, J.M. Evolutionary tuning impacts the design of bacterial tRNAs for the incorporation of unnatural amino acids by ribosomes. Current Opinion in Chemical Biology, 2018.
- Bayas, C.A., Wang, J., Lee, M.K., Schrader, J.M., Shapiro, L., Moerner, W.E. Spatial organization and dynamics of RNase E and ribosomes in Caulobacter crescentus. Proceedings of the National Academy of Sciences, 2018.
- Schrader, J.M., Li, G.W., Childers, W.S., Perez, A., Weissman, J.S., Shapiro, L., McAdams, H.H. Dynamic translational regulation in Caulobacter cell cycle control. Proceedings of the National Academy of Sciences 2016.
- Lasker, K.*, Schrader, J.M.*, Men, Y., Marshik, T., Dill, D.L., McAdams, H.H., Shapiro, L. CauloBrowser: a systems biology resource for Caulobacter crescentus. Nucleic Acids Research, 2016. *Equal contribution
- Zhou, B.*, Schrader, J.M.*, Kalogeraki, V.S., Abeliuk, E.A., Dinh, C.B., McAdams, H.H., Shapiro, L. The global regulatory architecture of transcription during the Caulobacter cell cycle. PLOS Genetics, 2015. *Equal contribution
- Schrader, J.M., Shapiro, L. Synchronization of Caulobacter crescentus for investigation of the bacterial cell cycle. JoVE, 2014.
- Liu, W., Kavaliauskas, D., Schrader, J.M., Perla-Kajan, J., Mandecki, W., Uhlenbeck, O.C., Knudsen, C.R., Goldman, Y.E., Cooperman, B.S. Labeled EF-Tus for rapid kinetic studies of pre-translocation complex formation. ACS Chemical Biology, 2014.
- Yikilmaz, E., Chapman, S.J., Schrader, J.M., Uhlenbeck, O.C. The interface between Escherichia coli Elongation Factor Tu and aminoacyl-tRNA. Biochemistry, 2014.
- Schrader, J.M., Zhou, B., Li, G., Lasker, K., Childers, W.S., Williams, B., Long, T., Crosson, S., McAdams, H.H., Weissman, J.S., Shapiro, L. The coding and noncoding architecture of the Caulobacter crescentus genome. PLOS Genetics, 2014.
- Chapman, S.J., Schrader, J.M., Uhlenbeck, O.C. Histidine 66 in E. coli elongation factor Tu selectively stabilizes aminoacyl-tRNAs. Journal of Biological Chemistry, 2011.
- Schrader, J.M., Uhlenbeck, O.C. Is the sequence-specific binding of aminoacyl-tRNAs by EF-Tu universal among bacteria?. Nucleic Acids Research, 2011.
- Schrader, J.M.,Chapman, S.J., Uhlenbeck, O.C. Tuning the affinity of aminoacyl-tRNA to elongation factor Tu for optimal decoding. Proceedings of the National Academy of Sciences, 2011.
- Schrader, J.M., Saks, M.E., Uhlenbeck, O.C. The specific interaction between aminoacyl-tRNAs and elongation factor Tu. Chapter 15. Ribosomes: Structure, Function, and Dynamics, 2010.
- Schrader, J.M.,Chapman, S.J., Uhlenbeck, O.C. Understanding the sequence specificity of tRNA binding to elongation factor Tu using tRNA mutagenesis. Journal of Molecular Biology, 2009.